吴川六

发布日期:2016-11-10     浏览次数:次   

威尼斯城娱乐官方平台

课题组主页: http://chlwu.xmu.edu.cn
邮箱: chlwu@xmu.edu.cn
办公室:化学楼535
电话:0592-2183206

个人简历:
博士(威尼斯城所有登入网址,2005-2010)
学士(威尼斯城所有登入网址,2001-2005)
研究助理(新加坡国立大学,2008-2009)
博士后(瑞士苏黎世联邦理工学院,2010-2012)

ETH Fellow(2010)

研究兴趣:
多肽分子探针;荧光探针;多肽/蛋白递送系统;蛋白质–多肽分子相互作用;生物分子识别机制

近期主要代表论著:

1. Yunyang Ling,? Jing Ren,? Tao Li, Yibing Zhao and Chuanliu Wu*, POEGMA-Based Disulfide-Containing Fluorescent Probes for Imitating and Tracing Noninternalization-Based Intracellular Drug Delivery, Chem. Commun., 2016, 52, 4533?4536.
2. Yiwu Zheng, Linxiang Zhai, Yibing Zhao, and Chuanliu Wu*, Orthogonal Cysteine-Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides, J. Am. Chem. Soc., 2015, 137, 15094?15097.
3. Yujie Li,? Tao Li,? Jinghui Wang, Xiaojia Bao, Yibing Zhao, and Chuanliu Wu*, Multivalent Peptides Displayed on OEGMA-based Copolymers for the Modulation of Protein-Protein Interactions, Polym. Chem., 2015, 6, 7862?7870.
4. Yaqi Chen,? Chaoqiong Yang,? Tao Li, Miao Zhang, Yang Liu, Marc A. Gauthier, Yibing Zhao, and Chuanliu Wu*, The Interplay of Disulfide Bonds, α-Helicity, and Hydrophobic Interactions Leads to Ultrahigh Proteolytic Stability of Peptides, Biomacromolecules, 2015, 16, 2347?2355.
5. Linxiang Zhai, Jingjing Liang, Xiangqun Guo, Yibing Zhao, and Chuanliu Wu*, Extraordinary Modulation of Disulfide Redox-Responsiveness by Cooperativity of Twin-Disulfide Bonds, Chem. Eur. J., 2014, 20, 17507?17514.
6. Chuanliu Wu,? Shuo Wang,? Lorine Bru?lisauer, Jean-Christophe Leroux, and Marc A. Gauthier*, Broad Control of Disulfide Stability through Microenvironmental Effects and Analysis in Complex Redox Environments, Biomacromolecules, 2013, 14, 2383?2388.
7. Chuanliu Wu, Jean-Christophe Leroux,* and Marc A. Gauthier*, Twin Disulfides for Orthogonal Disulfide Pairing and the Directed Folding of Multicyclic Peptides, Nature Chem., 2012, 4, 1044?1049.
8. Chuanliu Wu, Cristina Belenda, Jean-Christophe Leroux, and Marc A. Gauthier*, Interplay of Chemical Microenvironment and Redox Environment on Thiol–Disulfide Exchange Kinetics, Chem. Eur. J., 2011, 17, 10064?10070.


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